Deep Learning-Based Prediction Model for Monkeypox Detection
DOI:
https://doi.org/10.65890/race.v2i1.159Keywords:
Monkeypox Detection, Convolutional Neural Network, Image Segmentation, Transfer Learning, MobileNetV2, VGG16, U-Net, Deep LearningAbstract
Monkeypox is an emerging zoonotic viral disease caused by the Monkeypox virus (MPXV), which gained global attention following the unprecedented 2022 outbreak. The rapid spread of the disease across multiple continents highlighted the urgent need for efficient, scalable, and accessible diagnostic tools. This study proposes a deep learning-based prediction model for the automated detection of Monkeypox from skin lesion images, aimed at supporting early diagnosis, particularly in resource-constrained and rural healthcare settings. The proposed system employs a U-Net-based segmentation framework to isolate infected lesion regions, followed by Convolutional Neural Network (CNN) classifiers trained on a curated dataset of over 300 labelled images encompassing Monkeypox, Chickenpox, and healthy skin samples. To enhance model robustness and generalization, preprocessing techniques including noise reduction, normalization, and data augmentation were systematically applied. Several state-of-the-art transfer learning architectures, including AlexNet, VGG16, ResNet, InceptionNet, and MobileNetV2, were evaluated and benchmarked under uniform training conditions. The model demonstrates promising classification performance and holds significant potential for deployment as a mobile or web-based diagnostic aid, bridging critical gaps in healthcare accessibility worldwide.
References
[1] Moss, W. J., Shendale, S., Lindstrand, A., O'Brien, K. L., Turner, N., Goodman, T., & Kretsinger, K. (2021). Feasibility assessment of measles and rubella eradication. Vaccine, 39(27), 3544-3559. DOI: https://doi.org/10.1016/j.vaccine.2021.04.027
[2] Centers for Disease Control and Prevention, “Monkeypox”, https://www.cdc.gov/monkeypox/index.html (Accessed on 31/08/2025)
[3] Ravì, D., Wong, C., Deligianni, F., Berthelot, M., Andreu-Perez, J., Lo, B., & Yang, G. Z. (2016). Deep learning for health informatics. IEEE journal of biomedical and health informatics, 21(1), 4-21. DOI: https://doi.org/10.1109/JBHI.2016.2636665
[4] Shorten, C., & Khoshgoftaar, T. M. (2019). A survey on image data augmentation for deep learning. Journal of big data, 6(1), 1-48. DOI: https://doi.org/10.1186/s40537-019-0197-0
[5] Pan, S. J., & Yang, Q. (2009). A survey on transfer learning. IEEE Transactions on knowledge and data engineering, 22(10), 1345-1359. DOI: https://doi.org/10.1109/TKDE.2009.191
[6] Simonyan, K., & Zisserman, A. (2014). Very deep convolutional networks for large-scale image recognition. arXiv preprint arXiv:1409.1556.
[7] He, K., Zhang, X., Ren, S., & Sun, J. (2016). Deep residual learning for image recognition. In Proceedings of the IEEE conference on computer vision and pattern recognition (pp. 770-778). DOI: https://doi.org/10.1109/CVPR.2016.90
[8] Szegedy, C., Vanhoucke, V., Ioffe, S., Shlens, J., & Wojna, Z. (2016). Rethinking the inception architecture for computer vision. In Proceedings of the IEEE conference on computer vision and pattern recognition (pp. 2818-2826). DOI: https://doi.org/10.1109/CVPR.2016.308
[9] Glock, K., Napier, C., Gary, T., Gupta, V., Gigante, J., Schaffner, W., & Wang, Q. (2021, December). Measles rash identification using transfer learning and deep convolutional neural networks. In 2021 IEEE International Conference on Big Data (Big Data) (pp. 3905-3910). IEEE. DOI: https://doi.org/10.1109/BigData52589.2021.9671333
[10] Hosny, K. M., Kassem, M. A., & Foaud, M. M. (2019). Classification of skin lesions using transfer learning and augmentation with Alex-net. PloS one, 14(5), e0217293. DOI: https://doi.org/10.1371/journal.pone.0217293
[11] Ali, S. N., Ahmed, M. T., Paul, J., Jahan, T., Sani, S. M., Noor, N., & Hasan, T. (2022). Monkeypox skin lesion detection using deep learning models: A feasibility study. arXiv preprint arXiv:2207.03342.
[12] Bala, D. (2022). Monkeypox Skin Images Dataset (MSID) [Dataset]. Kaggle. https://doi.org/10.34740/KAGGLE/DSV/3971903.
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